• Poly(azomethine) Based Micelles for Delivery of Caffeic Acid Phenethyl Ester

  • Nermin Saliha Topuzogullari, Fatma Sayan Poyraz, Murat Topuzogullari*, and Banu Mansuroglu† 

  • Yildiz Technical University, Faculty of Arts and Sciences, Department of Molecular Biology and Genetics, 34220, Türkiye
    *Yildiz Technical University, Faculty of Chemical and Metallurgical Engineering, Department of Bioengineering, 34220, Türkiye

  • Cafferic Acid Phenethyl Ester 전달을 위한 Poly(azomethine) 기반 마이셀 연구

  • Reproduction, stored in a retrieval system, or transmitted in any form of any part of this publication is permitted only by written permission from the Polymer Society of Korea.

References
  • 1. Ulery, B. D.; Nair, L. S.; Laurencin, C. T. Biomedical Applications of Biodegradable Polymers. J. Polym. Sci. Part B: Polym. Phys. 2011, 49, 832-864.
  •  
  • 2. Von Burkersroda, F.; Schedl, L.; Göpferich, A. Why Degradable Polymers Undergo Surface Erosion or Bulk Erosion. Biomaterials 2002, 23, 4221-4231.
  •  
  • 3. Xin, Y.; Yuan, J. Schiff's Base as a Stimuli-responsive Linker in Polymer Chemistry. Polym. Chem. 2012, 3, 3045-3055.
  •  
  • 4. Baran, N. Y.; Saçak, M. Synthesis, Characterization and Molecular Weight Monitoring of a Novel Schiff Base Polymer Containing Phenol Group: Thermal Stability, Conductivity and Antimicrobial Properties. J. Molecul. Struct. 2017, 1146, 104-112.
  •  
  • 5. Mura, S.; Nicolas, J.; Couvreur, P. Stimuli-responsive Nanocarriers for Drug Delivery. Nat. Mater. 2013, 12, 991-1003.
  •  
  • 6. Duan, S.; Yuan, W.; Wu, F.; Jin, T. Polyspermine Imidazole-4, 5-imine, a Chemically Dynamic and Biologically Responsive Carrier System for Intracellular Delivery of siRNA. Ang. Chem. 2012, 32, 8062-8065.
  •  
  • 7. Dhers, S.; Vantomme, G.; Avérous, L. A Fully Bio-based Polyimine Vitrimer Derived from Fructose. Green Chem. 2019, 21, 1596-1601.
  •  
  • 8. Jiang, X.; Ai, Y.; Han, Z.; You, Y.; Luo, H.; Cui, J.; Wei, F.; Fu, J.; He, Q.; Cheng, J. Block Copolymer-directed Synthesis of Conjugated Polyimine Nanospheres with Multichambered Mesopores. Macromol. Chem. Phys. 2020, 221, 2000061.
  •  
  • 9. Ma, B.; Zhuang, W.; Liu, G.; Wang, Y. A Biomimetic and pH-sensitive Polymeric Micelle as Carrier for Paclitaxel Delivery. Regen. Biomater. 2018, 5, 15-24.
  •  
  • 10. Sun, X.-M.; Xu, J.-X.; Tang, J.-B.; Sui, M.-H.; Shen, Y.-Q. Folate-targeted Optical and Magnetic Resonance Dualmodality PCL-b-PEG Micelles for Tumor Imaging. Chinese J. Polym. Sci. 2011, 29, 427-430.
  •  
  • 11. Hoang Thi, T. T.; Pilkington, E. H.; Nguyen, D. H.; Lee, J. S.; Park, K. D.; Truong, N. P. The Importance of Poly(ethylene glycol) Alternatives for Overcoming PEG Immunogenicity in Drug Delivery and Bioconjugation. Polymers 2020, 12, 298.
  •  
  • 12. Kwon, G. S.; Kataoka, K. Block Copolymer Micelles as Long-circulating Drug Vehicles. Adv. Drug. Delivery Rev. 2012, 64, 237-245.
  •  
  • 13. Torchilin, V. Tumor Delivery of Macromolecular Drugs Based on the EPR Effect. Adv. Drug Delivery Rev. 2011, 63, 131-135.
  •  
  • 14. Ozyurt, H.; Irmak, M. K.; Akyol, O.; Söğüt, S. Caffeic Acid Phenethyl Ester Changes the Indices of Oxidative Stress in Serum of Rats with Renal Ischaemia-reperfusion Injury. Cell. Biochem. Funct. 2001, 19, 259-263.
  •  
  • 15. Ozer, M.; Parlakpinar, H.; Acet, A. Reduction of Ischemia–reperfusion Induced Myocardial Infarct Size in Rats by Caffeic Acid Phenethyl Ester (CAPE). Clin. Biochem. 2004, 37, 702-705.
  •  
  • 16. Nah, J.-W.; Paek, Y.-W.; Jeong, Y.-I.; Kim, D.-W.; Cho, C.-S.; Kim, S.-H.; Kim, M.-Y. Clonazepam Release From Poly(DL-lactide-co-glycolide) Nanoparticles Prepared by Dialysis Method. Arch. Pharm. Res. 1998, 21, 418-422.
  •  
  • 17. Dutta, P.; Jain, P.; Sen, P.; Trivedi, R.; Sen, P.; Dutta, J. Synthesis and Characterization of a Novel Polyazomethine Ether for NLO Application. Europ. Polym. J. 2003, 39, 1007-1011.
  •  
  • 18. Kamaci, U. D.; Kamaci, M.; Peksel, A. Poly(azomethine-urethane) and Zeolite-based Composite: Fluorescent Biosensor for DNA Detection. Spectroch. Acta Part A: Molecul. Biomol. Spectrosc. 2019, 212, 232-239.
  •  
  • 19. Bekri, I.; Gherras, H., Dehbi, A.; Belfedal, A. Preparation and Characterization of New Soluble and Thermally Stable Polyazomethine by Polycondensation of Thiophene-2,5-dicarboxaldehyde and Ortho-tolidine for Optoelectronics. Polym. Sci. Series B 2023, 65, 487-495.
  •  
  • 20. Xiong, D. A.; He, Z.; An, Y.; Li, Z.; Wang, H.; Chen, X.; Shi, L. Temperature-responsive Multilayered Micelles Formed From the Complexation of PNIPAM-b-P4VP Block-copolymer and PS-b-PAA Core–shell Micelles. Polymer 2008, 49, 2548-2552.
  •  
  • 21. Kim, S.; Shi, Y.; Kim, J. Y.; Park, K.; Cheng, J.-X. Overcoming the Barriers in Micellar Drug Delivery: Loading Efficiency, in vivo Stability, and Micelle–cell Interaction. Expert Opin. Drug Deliv. 2010, 7, 49-62.
  •  
  • 22. Arasoglu, T.; Derman, S.; Mansuroglu, B. Comparative Evaluation of Antibacterial Activity of Caffeic Acid Phenethyl Ester and PLGA Nanoparticle Formulation by Different Methods. Nanotechnology 2015, 27, 025103.
  •  
  • 23. Hosonuma, M.; Yoshimura, K. Association Between pH Regulation of the Tumor Microenvironment and Immunological State. Frontiers in Oncology 2023, 13, 1175563.
  •  
  • 24. Zeng, J.; Shirihai, O. S.; Grinstaff, M. W. Modulating Lysosomal pH: a Molecular and Nanoscale Materials Design Perspective. J. Life Sci. 2020, 2, 25-37.
  •  
  • 25. De Witte, T.-M.; Wagner, A. M.; Fratila-Apachitei L. E.; Zadpoor, A. A.; Peppas, N. A. Degradable Poly(methyl methacrylate)-co-methacrylic Acid Nanoparticles for Controlled Delivery of Growth Factors for Bone Regeneration. Tissue Eng. Part A 2020, 26, 23-24.
  •  
  • 26. Saracoglu, P.; Dokuz, S.; Ozbek, T.; Topuzogullari, M.; Ozmen, M. M. Starch Nanogels as Promising Drug Nanocarriers in the Management of Oral Bacterial Infections. J. Drug Deliv. Sci. Technol. 2023 88, 104973.
  •  
  • 27. Hoffmann, S.; Gorzelanny, C.; Moerschbacher, B.; Goycoolea, F. M. Physicochemical Characterization of FRET-labelled Chitosan Nanocapsules and Model Degradation Studies. Nanomaterials 2018, 8, 846.
  •  
  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 2234-8077(Online)
    Abbr. Polym. Korea
  • 2023 Impact Factor : 0.4
  • Indexed in SCIE

This Article

  • 2025; 49(3): 277-284

    Published online May 25, 2025

  • 10.7317/pk.2025.49.3.277
  • Received on Jul 9, 2024
  • Revised on Nov 25, 2024
  • Accepted on Dec 24, 2024

Correspondence to

  • Banu Mansuroglu

  • Yildiz Technical University, Faculty of Arts and Sciences, Department of Molecular Biology and Genetics, 34220, Türkiye

  • E-mail: bmansur@yildiz.edu.tr