• Structure and Properties of Gelatin Hydrogels Immersed in Ammonium Ferric Citrate Solutions

  • Xiaomin Wang, Congde Qiao† , Qian Lu, Qinze Liu, Wenke Yang† , and Jinshui Yao

  • School of Materials Science and Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, PR China

  • 구연산 철 암모늄 용액에 침지된 젤라틴 하이드로젤의 구조 및 물성

  • Reproduction, stored in a retrieval system, or transmitted in any form of any part of this publication is permitted only by written permission from the Polymer Society of Korea.


References
  • 1. He, Q.; Huang, Y.; Wang, S.; Hofmeister Effect-Assisted One Step Fabrication of Ductile and Strong Gelatin Hydrogels. Adv. Func. Mater. 2018, 28, 1705069.
  •  
  • 2. Wang, X. J.; Qiao, C. D.; Jiang, S.; Liu, L. B.; Yao, J. S. Wang, X. Hofmeister Effect in Gelatin-based Hydrogels with Shape Memory Properties. Colloid. Surface. B 2022, 217, 112674.
  •  
  • 3. Qin, Z. H.; Dong, D. Y.; Yao, M. M.; Yu, Q. Y.; Sun, X.; Guo, Q.; Zhang, H. T.; Yao, F. L.; Li, J. J. Freezing-Tolerant Supramolecular Organohydrogel with High Toughness, Thermoplasticity, and Healable and Adhesive Properties. ACS Appl. Mater. Interfaces 2019, 11, 21184-21193.
  •  
  • 4. Jiang, L. B.; Su, D. H.; Ding, S. L.; Zhang, Q. C.; Li, Z. F.; Chen, F. C.; Ding, W.; Zhang, S. T.; Dong, J. Salt-assisted Toughening of Protein Hydrogel with Controlled Degradation for Bone Regeneration. Adv. Func. Mater. 2019, 29, 1901314.
  •  
  • 5. Hellio, D.; Djabourov, M.; Physically and Chemically Crosslinked Gelatin Gels. Macromol. Symp. 2006, 241, 23-27.
  •  
  • 6. Van Den Bulcke, A. I.; Bogdanov, B.; De Rooze, N.; Schacht, E. H.; Cornelissen, M.; Berghmans, H. Structural and Rheological Properties of Methacrylamide Modified Gelatin Hydrogels. Biomacromolecules 2000, 1, 31-38.
  •  
  • 7. Balakrishnan, B.; Mohanty, M.; Umashankar, P. R.; Jayakrishnan, A. Evaluation of An In Situ Forming Hydrogel Wound Dressing Based on Oxidized Alginate and Gelatin. Biomaterials 2005, 26, 6335-6342.
  •  
  • 8. Derkach, S. R.; Voron'ko, N. G.; Kuchina, Y. A.; Kolotova, D. S.; Gordeeva, A. M.; Faizullin, D. A.; Gusev, Y. A.; Zuev, Y. F.; Makshakova, O. N. Molecular Structure and Properties of κ-carrageenan-gelatin Gels. Carbohydr. Polym. 2018, 197, 66-74.
  •  
  • 9. Zhang, H. J.; Wang, L.; Wang, X.; Han, Q.; You, X. Developing Super Tough Gelatin-based Hydrogels by Incorporating Linear Poly(methacrylic acid) to Facilitate Sacrificial Hydrogen Bonding. Soft. Matter. 2020, 16, 4723-4727.
  •  
  • 10. Wan, C.; Frydrych, M.; Chen, B. Strong and Bioactive Gelatin-graphene Oxide Nanocomposites. Soft. Matter. 2011, 7, 6159-6166.
  •  
  • 11. Li, H.; Wang, D. Q.; Liu, B. L.; Gao, L. Z. Synthesis of a Novel Gelatin-carbon Nanotubes Hybrid Hydrogel. Colloids Surf. B Biointerfaces 2004, 33, 85-88.
  •  
  • 12. Gong, J. P.; Katsuyama, Y.; Kurokawa, T.; Osada, Y. Double-network Hydrogels with Extremely High Mechanical Strength. Adv. Mater. 2003, 15, 1155-1158.
  •  
  • 13. Gong, J. P. Why are Double Network Hydrogels so Tough?. Soft. Matter. 2010, 6, 2583-2590.
  •  
  • 14. Wang, Z. J.; Jiang, J. L.; Mu, Q. F.; Maeda, S.; Nakajima, T.; Gong, J. P. Azo-Crosslinked Double-Network Hydrogels Enabling Highly Efficient Mechanoradical Generation. J. Am. Chem. Soc. 2022, 144, 3154-3161.
  •  
  • 15. Samp, M. A.; Iovanac, N. C.; Nolte, A. J. Sodium Alginate Toughening of Gelatin Hydrogels. ACS Biomater. Sci. Eng. 2017, 3, 3176-3182.
  •  
  • 16. Ren, J.; Wang, X.; Zhao, L.; Li, M.; Yang, W. Double Network Gelatin/chitosan Hydrogel Effective Removal of Dyes from Aqueous Solutions. J. Polym. Environ. 2022,30, 2007-2021.
  •  
  • 17. Sun, J. S.; Sun, M. Y.; Zang, J. C.; Zhang, T.; Lv, C. Y.; Zhao, G. H. Highly Stretchable, Transparent, and Adhesive Double-Network Hydrogel Dressings Tailored with Fish Gelatin and Glycyrrhizic Acid for Wound Healing. ACS Appl. Mater. Interfaces 2023, 15, 42304-42316.
  •  
  • 18. Yan, X. Q.; Chen, Q.; Zhu, L.; Chen, H.; Wei, D. D.; Chen, F.; Tang, Z. Q.; Yang, J.; Zheng, J. High Strength and Self-healable Gelatin/polyacrylamide Double Network Hydrogels. J. Mater. Chem. B 2017, 5, 7683-7691.
  •  
  • 19. Tang, L.; Zhang, D.; Gong, L.; Zhang, Y. X.; Xie, S. W.; Ren, B. Q.; Liu, Y. L.; Yang, F. Y.; Zhou, G. Y.; Chang, Y.; Tang, J. X.; Zheng, J. Double-Network Physical Cross-Linking Strategy To Promote Bulk Mechanical and Surface Adhesive Properties of Hydrogels. Macromolecules 2019,52, 9512-9525.
  •  
  • 20. Wang, X. J.; Qiao, C. D.; Jiang, S.; Liu, L. B.; Yao, J. S. Strengthening Gelatin Hydrogels Using the Hofmeister Effect. Soft. Matter. 2021,17, 1558-1565.
  •  
  • 21. Chen, H. R.; Shi, P. J.; Fan, F. J.; Chen, H.; Wu, C.; Xu, X. B.; Wang, Z. Y.; Du, M. Hofmeister Effect-assisted One Step Fabrication of Fish Gelatin Hydrogels. LWT 2020,121, 108973.
  •  
  • 22. Liu, C.; Zhang, H. J.; You, X.; Cui, K.; Wang, X. Electrically Conductive Tough Gelatin Hydrogel. Adv. Electron. Mater 2020, 6, 2000040.
  •  
  • 23. Qin, Z. H.; Sun, X.; Zhang, H. T.; Yu, Q. Y.; Wang, X. Y.; He, S. S.; Yao, F. L.; Li, J. J. A Transparent, Ultrastretchable and Fully Recyclable Gelatin Organohydrogel Based Electronic Sensor with Broad Operating Temperature. J. Mater. Chem. A 2020,8, 4447-4456.
  •  
  • 24. Sun, X.; Yao, F. L.; Wang, C. Y.; Qin, Z. H.; Zhang, H. T.; Yu, Q. Y.; Zhang, H.; Dong, X. R.; Wei, Y. P.; Li, J. J. Ionically Conductive Hydrogel with Fast Self-Recovery and Low Residual Strain as Strain and Pressure Sensors. Macromol. Rapid Commun. 2020, 41, 2000185.
  •  
  • 25. Chen, F.; Yang, K. X.; Zhao, D. L.; Yang, H. Y. Thermal- and Salt-activated Shape Memory Hydrogels Based on a Gelatin/polyacrylamide Double Network. RSC. Adv. 2019, 9, 18619-18626.
  •  
  • 26. Jaspers, M.; Rowan, A. E.; Kouwer, P. H. J. Tuning Hydrogel Mechanics Using the Hofmeister Effect. Adv. Funct. Mater. 2015,25, 6503-6510.
  •  
  • 27. Yu, D. S.; Yi, J.; Zhu S. H.; Tang, Y. H.; Huang, Y. Y.; Lin, D.; Lin, Y. H.; Hofmeister Effect-Assisted Facile One-Pot Fabrication of Double Network Organohydrogels with Exceptional Multi-Functions. Adv. Funct. Mater. 2024, 34, 2307566.
  •  
  • 28. Luo, B.; Cai, C. C.; Liu, T.; Meng X. J.; Zhuang, X. L.; Liu, Y. H.; Gao, C.; Chi, M. C.; Zhang, S.; Wang, J. L.; Bai, Y. Y.; Wang, S. F.; Nie. S. X. Multiscale Structural Nanocellulosic Triboelectric Aerogels Induced by Hofmeister Effect. Adv. Funct. Mater. 2023,33, 2306810.
  •  
  • 29. Wang, J. R.; Fan, X. L.; Liu, H.; Tang, K. Y. Self-assembly and Metal Ions-assisted One Step Fabrication of Recoverable Gelatin Hydrogel with High Mechanical Strength. Polym-Plast. Tech. Mat. 2020, 59, 1899-1909.
  •  
  • 30. Lin, J. H.; Du, X. S. Self-healable and Redox Active Hydrogel Obtained via Incorporation of Ferric Ion for Supercapacitor Applications. Chem. Eng. J. 2022, 446, 137244.
  •  
  • 31. Zheng, S. Y.; Ding, H.; Qian, J.; Yin, J.; Wu, Z. L.; Song, Y. H.; Zheng, Q. Metal Coordination Complexes Mediated Physical Hydrogels with High Toughness, Stick–slip Tearing Behavior, and Good Processability. Macromolecules 2016,49, 9637-9646.
  •  
  • 32. Zhang, H. M.; Xue, K.; Shao, C. Y.; Hao, S. W.; Yang, J. Recent Progress in Bioinspired Design Strategies for Freeze Resistant Hydrogel Platforms toward Flexible Electronics. Chem. Mater. 2023, 35, 10316-10347.
  •  
  • 33. Morelle, X. P.; Illeperuma, W. R.; Tian, K.; Bai, R. B.; Suo, Z. G.; Vlassak, J. J. Highly Stretchable and Tough Hydrogels below Water Freezing Temperature. Adv. Mater. 2018, 30, 1801541.
  •  
  • 34. Chen, H.; Ren, X.; Gao, G. Skin-inspired Gels with Toughness, Antifreezing, Conductivity, and Remoldability. ACS Appl. Mater. Interfaces 2019, 11, 28336-28344.
  •  
  • 35. Sang, M.; Wang, J. J.; Zuo, D. Y.; Xu, J.; Zhang, H. W.; Li, H. J.; Eutectogel with (NH4)2SO4-Based Deep Eutectic Solvent for Ammonium-Ion Supercapacitors. ACS Sustainable Chem. Eng. 2024, 12, 2455-2464.
  •  
  • 36. Liu, R. P.; Qiao, C. D.; Liu, Q. Z.; Liu, L. B.; Yao, J. S. Fabrication and Properties of Anti-freezing Gelatin Hydrogels Based on a Deep Eutectic Solvent. ACS Appl. Polym. Mater. 2023,5, 4546-4553.
  •  
  • 37. Chen, F.; Zhou, D.; Wang, J. H.; Li, T. Z.; Zhou, X. H.; Gan, T. S.; Handschuh-Wang, S.; Zhou, X. C. Rational Fabrication of Anti-Freezing, Non-Drying Tough Organohydrogels by One-Pot Solvent Displacement. Angew. Chem. 2018, 130, 6678-6681.
  •  
  • 38. Hashim, D. M.; Che Man, Y. C.; Norakasha, R.; Shuhaimi, M.; Salmah, Y.; Syahariza, Z. A. Potential use of Fourier Transform Infrared Spectroscopy for Differentiation of Bovine and Porcine Gelatins. Food. Chem. 2010,118, 856-860.
  •  
  • 39. Li, C. H.; Wang, C.; Keplinger, C.; Zuo, J. L.; Jin, L. H.; Sun, Y.; Zheng, P.; Cao, Y.; Lissel, F.; Linder, C.; You, X. Z.; Bao, Z. N. A Highly Stretchable Autonomous Self-healing Elastomer. Nat. Chem. 2016, 8, 618-624.
  •  
  • 40. Wang, Z. H.; Xie, C.; Yu, C. J.; Fei, G. X.; Wang, Z. H.; Xia, H. S. A Facile Strategy for Self-Healing Polyurethanes Containing Multiple Metal-Ligand Bonds. Macromol. Rapid. Commun. 2018,39, 1700678.
  •  
  • 41. Yu, P.; Li, Y. Y.; Sun, H.; Ke, X.; Xing, J. Q.; Zhao, Y. R.; Xu, X. Y.; Qin, M.; Xie, J.; Li, J. S. Cartilage-Inspired Hydrogel with Mechanical Adaptability, Controllable Lubrication, and Inflammation Regulation Abilities. ACS Appl. Mater. Interfaces 2022,14, 27360-27370.
  •  
  • 42. Tan, Q. W.; Li, P.; Han, K.; Liu, Z. W.; Li, Y.; Zhao, W.; He, D. L.; An, F. Q.; Qin, M. L.; Qu, X. H. Chemically Bubbled Hollow FexO Nanospheres Anchored on 3D N-doped Few-layer Graphene Architecture as a Performance-enhanced Anode Material For Potassium-ion Batteries. J. Mater. Chem. A 2019, 7, 744-754.
  •  
  • 43. Xue, Y. R.; Liu, C.; Ma, Z. Y.; Zhu, C. Y.; Wu, J.; Liang, H. Q.; Yang, H. C.; Zhang, C.; Xu, Z. K. Harmonic Amide Bond Density as a Gamechanger for Deciphering the Crosslinking Puzzle of Polyamide. Nat. Commun. 2024,15, 1539.
  •  
  • 44. Gornall, J. L.; Terentjev, E. M. Helix-coil Transition of Gelatin: Helical Morphologyand Stability. Soft. Matter. 2008, 4, 544-549.
  •  
  • 45. Pezron, I.; Djabourov, M.; Bosio, L.; Leblond, J. X-ray Diffraction of Gelatin Fibers in the Dry and Swollen States. J. Polym. Sci. Part B: Polym. Phys. 1990, 28, 1823-1839.
  •  
  • 46. Ovando-Roblero, A.; Meza-Gordillo, R.; Castañeda-Valbuena, D.; Castañó-González, J. H.; Ruiz-Valdiviezo, V. M.; Gutiérrez-Santiago, R.; Grajales-Lagunes, A. Metal-chelated Biomaterial From Collagen Extracted From Pleco Skin (Pterygoplichthys pardalis). SN Appl. Sci. 2023, 5, 321.
  •  
  • 47. Bigi, A.; Panzavolta, S.; Rubini, K. Relationship Between Triple-helix Content and Mechanical Properties of Gelatin Films. Biomaterials 2004,25, 5675-5680.
  •  
  • Polymer(Korea) 폴리머
  • Frequency : Bimonthly(odd)
    ISSN 2234-8077(Online)
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This Article

  • 2026; 50(1): 49-59

    Published online Jan 25, 2026

  • 10.7317/pk.2026.50.1.49
  • Received on Jun 10, 2025
  • Revised on Sep 15, 2025
  • Accepted on Oct 14, 2025

Correspondence to

  • Congde Qiao, Wenke Yang

  • School of Materials Science and Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, PR China

  • E-mail: cdqiao@qlu.edu.cn, yangwen_ke@126.com